Royal Air Force Typhoon fighter aircraft have operated alongside French aircraft in a combined operation targeting an hidden munitions depot in Syria used by the IS group, per a report from the UK's MoD.
The location, pinpointed through intelligence, was assessed as containing munitions and bombs, the announcement noted, and was positioned in hills just to the north of Palmyra in the heart of Syria.
"The RAF jets used precision-guided Paveway IV munitions to strike a number of entry passages providing entry to the facility... initial indications indicate the objective was successfully hit," officials stated.
There was no evidence of any civilian casualties in the strike conducted Saturday night and every plane involved returned safely, the ministry further stated.
The Typhoon fighters were backed up by a Voyager refuelling tanker.
IS - referred to as the so-called Islamic State - established extremist governance over parts of Syria and Iraq prior to its 2019 collapse.
"This action underscores the UK's leading role, and determination to work closely with allied nations, to eradicate any re-emergence of Daesh and their dangerous and violent ideologies in the region," UK Defence Secretary John Healey remarked.
RAF aircraft have carried out surveillance missions over Syria to "prevent any attempted comeback" of IS after its military defeat at the climactic battle in Baghuz in 2019, the ministry said.
"I must thank the personnel of our armed forces involved in this mission for their professionalism and their bravery," the Defence Secretary said. "They were part of thousands of British troops stationed over Christmas and New Year. This action, to remove militants who pose a risk to our security, shows how our armed forces are always on standby, continuously, keeping Britain secure within its borders and strong abroad."
Last December, the United States armed forces conducted what it described as a "major assault" targeting Daesh sites in the country, after an assault killed two American soldiers and a civilian linguist in the Palmyra area.
The United Nations estimates Daesh still maintains roughly 5-7 thousand militants in Iraq and Syria.